WebCrystal Biopharmaceutical Llc Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2012-02-01 Filing date 2013-01-31 Publication date 2013-08-08 Priority claimed from US201261593459P external-priority WebMar 14, 2024 · The study aims to enhance the biopharmaceutical properties of norfloxacin, a water-insoluble antibacterial antibiotic, by synthesizing co-crystals using three co-formers: nicotinamide, cinnamic acid, and sorbic acid. ... The apparent solubility of all the co-crystals improved, and the IDR of the NF-NIC co-crystal increased about 6.53 times ...
WO2013113838A1 - Novel therapeutic agents - Google Patents
WebFeb 27, 2024 · Krystal Biotech, Inc. (NASDAQ: KRYS) is a biotechnology company focused on developing and commercializing genetic medicines for patients with rare diseases. The Company’s wide-ranging pipeline is … WebCrystal engineering, through supramolecular synthons, allows us to design cocrystals with desired physicochemical properties. 3-5 Cocrystallization 6-8 and polymorphism 9-11 are two important applications of crystal … michaels happy planner cover
Cocrystals of diacerein: Towards the development of improved ...
WebAug 1, 2024 · Pharmaceutical cocrystals are defined as crystals that comprise two or more discrete neutral molecules at a stoichiometric ratio and bond together via noncovalent bond interactions (e.g., hydrogen bonding, van der Waals and π···π stacking interactions), in which at least one of the components is API and the others are pharmaceutically … WebJun 1, 2024 · This review on the design, synthesis, and applications of pharmaceutical cocrystals to afford improved drug products and drug substances will interest researchers in crystal engineering, … WebThe biopharmaceutical studies confirmed that caspofungin was released following a one-phase exponential association model and the CPF-AZ gel showed a higher release. The CPF-AZ gel showed higher retention of caspofungin in the skin while limiting the diffusion of the drug to the receptor fluid. ... (ATR) with a diamond crystal. A total of 32 ... michael shaps wineworks extended